Dominic Cooper and Anthony Mackie are in talks to star in Twentieth Century Fox's adaption of Seth Grahame-Smith's "Abraham Lincoln: Vampire Hunter," according to Deadline.

Cooper ("The Devil's Double") would play Lincoln's mentor Henry, a mysterious man gifted with the craft of vampire slaying; Mackie ("The Adjustment Bureau") would take the role of Will, Lincoln's best friend.

Twentieth Century Fox had eyed Joaquin Phoenix ("Walk the Line") for the role of Henry before Cooper became the front runner.

Last month, Benjamin Walker signed aboard the project to play Abraham Lincoln. This is then second unconventional presidential role for Walker, who recently starred in Broadway's "Bloody Bloody Andrew Jackson."

Grahame-Smith's supernatural tale -- which he is penning for the screen -- centers on Lincoln's secret, lifelong vendetta against vampires following the death of his mother at their hands.

Set for a June 22, 2012 release, the 3-D film is budgeted at $69 million and will be helmed by Timur Bekmambetov ("Wanted"), with Tim Burton and Jim Lemley producing.

Bekmambetov, a Russian director, was introduced to audiences worldwide with his 2004 vampire film "Night Watch," which Fox also distributed.